Borderlands 4

It shares the essentials of what Sanctum does: a sci-fi setting, single-player focus and a first-person view. Its own ground is deep RPG systems.
Released 14 years after Sanctum.

Games like Sanctum · Find similar →
We filtered the 50 games similar to Sanctum down to the 4 that fit the “PS5” category. Borderlands 4, Overwatch and Fallout 76 top the list, ranked by affinity and similarity score to Sanctum.
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Within the “PS5” category, the closest game to Sanctum is Borderlands 4 — scoring 66/100 on our similarity scale. Overwatch and Fallout 76 follow close behind.
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Handpicked by our similarity algorithm, these are the titles with the highest gameplay match to Sanctum. Each one has been evaluated across 12 real attributes — from combat style and progression mechanics to world structure and visual perspective — so every recommendation is based on how the game actually plays, not just its genre label.

It shares the essentials of what Sanctum does: a sci-fi setting, single-player focus and a first-person view. Its own ground is deep RPG systems.
Released 14 years after Sanctum.

It meets Sanctum on a sci-fi setting, single-player focus and a first-person view. Its own ground is PvP competition and a third-person camera.
Released 12 years after Sanctum.

Same family as Sanctum: a sci-fi setting, multiplayer gameplay and a first-person view. The distance is in tone and setting — its own ground is dark, oppressive atmosphere and post-apocalyptic world.
Released 7 years after Sanctum.

What carries over from Sanctum is single-player focus and a first-person view. What it adds of its own: adventure storytelling and a sandbox world.
Released 3 years after Sanctum.
If Sanctum left you wanting more, this is where you narrow it down. Was it the casual or the sci-Fi that hooked you? There is a list of just that. And if you play on PS5, PlayStation and Xbox, filter by platform and skip the games you could not play anyway.
Sometimes what you want is not a Sanctum look-alike but simply the best FPS Games there are. That is what these rankings are for: no comparison to anything, just the highest-rated games. And if you feel like widening the net, the Shooter Games ranking is a good way to run into something you were not expecting.